USB Manager is a small Windows utility that can quickly enable and disable USB devices. It has no interface and runs from the system tray. You can control the devices from the right-click context menu.
It allows users to control USB devices such as, storage, printers, scanners, audio, and other devices.
It can also be used to lock a device. Suppose you want to disable printing, scanning, or a storage device, first disable it and then go to options to password protect the settings.
This can in fact be very useful. If you have a computer in office workspace and are worried that someone might copy a file then you can disable storage devices and password protect it. Once done, all USB inserted in your computer will fail to work.
There is also an option to enable hotkey, start with windows, and hide it from the system tray.
Download USB Manager (Site is in Russian, download link given directly below the heading)
It works on Windows 2000, Windows XP, Windows Vista, Windows Server 2003/2008, and Windows 7. Enjoy!